Disease - Proof That A Natural Extract Can Stop Eye Disease
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J. Michael Brown, Chairman of the Board.
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J. Michael Brown, Chairman
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Article Source: http://EzineArticles.com/?expert=J_Michael_Brown
A scientific study showed how it's possible to stop eye diseases. It is definitive proof that a naturally occurring substance could help stop some eye diseases.
A press release of July 31, 2007 by Sirtris Pharmaceuticals, Inc., which is a biopharmaceutical company based in Cambridge, Massachusetts and listed on the NASDAQ stock exchange as SIRT, focused on how it discovered a means to facilitate anti-aging; and specifically how to stop optic neuritis.
The findings, which presented definitive proof that eye diseases may be stopped with a naturally occurring substance, appeared in an article entitled "SIRT1 Activation Confers Neuroprotection in Experimental Optic Neuritis, Shindler et al., 2007" that was published in The Investigative Ophthalmology and Visual Science Journal (IOVS), Volume 48, Number 8.
Optic neuritis is an eye disease, which affects the optic nerve comprised of axons emerging from the retina of the eye. The optic nerve carries visual information to the main visual nuclei, of which is primarily relayed to the outer layer of the occipital lobe of the brain; where the brain processes information into vision.
Swelling of the optic nerve can result in loss of vision more often than not because the inflammation results in destruction of the myelin sheath, which covers the optic nerve. Uninterrupted axonal damage often plays a role in neural destruction.
Optic neuritis is commonly linked to conditions including:
The scientific study at Sirtris showed, that by developing small molecule interference, eye diseases could be stopped. Sirtris hopes that he substance used in the scientific study will be approved by the FDA to treat diseases related to aging like Type II Diabetes and Macular Degeneration.
The scientific study showed that activating the SIRT1 gene, which is an enzyme in the sirtuin family, with SRT501 (resveratrol); optic neuritis be relieved. Sirtris presented pictures related to the microscopic analysis of the optic nerves of mice, which they performed; after the mice initially were induced to have optic neuritis, then anesthetized--and finally the mice had the nerves leading to the occipital injected with the SIRT1 formula.
Sirtris offered the results of the experiment as definitive proof that resveratrol could be associated with anti-aging, and that their SIRT1 a formula was a debilitating factor when used to deter some eye diseases.
Resveratrol was the agent to which the scientists assigned credit for activation of the anti-aging gene SIRT1 in mice; and they took it one step further by inferring that humans could generally, and conveniently, become accustomed to the adaptation of resveratrol as a neuroprotective agent against optic neuritis.
Therefore, Sirtris offered the study as proof that eye diseases associated with optic neuritis in humans could be stopped too, simply by using resveratrol.
The gradually loss of neurons associated with age may bring about a various debilitating neurological disorders, one of which is optic neuritis. One of the initial signs of multiple sclerosis is optic neuritis, and it's been associated with a reduction of mitochondrial function.
Sirtuin, which is a new class of enzymes and only recently discovered, appears to influence the aging process in test mammals, and Sirtris offered the study under review as proof that it increases the number and fundamental operation of mitochondria.
According to results of the scientific study, resveratrol is an SIRT1 activator and it fundamentally deterred losing retinal ganglion cells in test animals; thereby preserving axonal function in a pre-clinical model of optic neuritis.
A single intravitreal injection of SRT501, which is the proprietary resveratrol formula developed by Sirtris, was adequate for neuroprotection. What's more; the neuroprotective effect was proof that activation of SIRT1 was the reason for the significant results because that was how sirtinol, which is a SIRT1 inhibitor, was blocked.
Peter Elliott, Ph.D. said, "This work is significant because it shows that a SIRT1 activator is neuroprotective and thus has the potential to be therapeutic for a range of neurodegenerative diseases of aging."
Christoph Westphal, M.D., Ph.D., who was the Chief Executive Officer of Sirtris Pharmaceuticals, Inc. until April 2010; added, "These new data support our belief in SIRT1 as a therapeutic target for a broad range of diseases of aging including metabolic, mitochondrial, and neurological disorders."
Sirtris Pharmaceuticals, a biopharmaceutical company, is focused on inventing and developing proprietary small molecule drugs, which can be administered by physicians via intravitreal injection; and the research project under review in this expose' concerns their SRT501 resveratrol formula.
Whether or not Sirtris plans to make their SRT501 formula available as an over-the-counter supplement remains to be seen.
But the question, which will remain unanswered in this editorial; is, "Can over-the-counter resveratrol stop many of the diseases that are associated with aging simply by taking a capsule of it once or twice a day, without a prescription from a medical doctor?"
Some of the diseases, which need to be considered in a future scientific study that could provide proof that such a miracle capsule would really work to stop eye diseases, include metabolic disorders such as:
The study wouldn't be limited to those diseases specifically, but it will look at overall general health of individuals.
People who would like to be candidates for such a study would have to understand that the nutritional supplements, one of which would include an over-the-counter formula with a substantial amount of resveratrol, would be formulated to mimic beneficial health effects that'd ultimately be equivalent to calorie restriction; without necessitating a change of eating habits.
Activation of the newly discovered class of enzymes, sirtuin, is the foundation upon which Sirtris has offered proof via several scientific studies; that resveratrol is an anti-aging agent. The company's headquarters are in Cambridge, Massachusetts.
The press release, upon which this article is based; contained forward-looking statements, which were contained in it that conform to the Private Securities Litigation Reform Act of 1995. Those statements included, but they weren't limited to, potential therapeutic benefits of resveratrol; and they have proof that it is an SIRT1 activator.
The US Food and Drug Administration (FDA) hasn't evaluated the statements contained within this commentary. Over-the-counter resveratrol supplements are not intended to prevent, diagnose, cure or treat any disease.
The sole purpose of over-the-counter resveratrol is to activate the SIRT1 gene, which in theory would allow people to age normally without maladies commonly associated with getting older; so, as the scientific study discussed in this editorial shows, it's how some people might stop some debilitating eye diseases.
The information provided in this expose' is for educational purposes only. The information contained herein is not meant to be a substitute for medical advice of physicians, or the advice of which any other medical professionals might provide.
The accounts contained within this document shouldn't be used as a basis to diagnose or treat any health problem and/or disease; nor should any product containing resveratrol be used as a substitution for a medication that's been prescribed by your physician.
Be sure to read all product packaging and labels carefully. If you think that you could have a medical problem, promptly consult a physician or a health care provider.
February 17, 2011 Copyright of J. Michael Brown
A press release of July 31, 2007 by Sirtris Pharmaceuticals, Inc., which is a biopharmaceutical company based in Cambridge, Massachusetts and listed on the NASDAQ stock exchange as SIRT, focused on how it discovered a means to facilitate anti-aging; and specifically how to stop optic neuritis.
The findings, which presented definitive proof that eye diseases may be stopped with a naturally occurring substance, appeared in an article entitled "SIRT1 Activation Confers Neuroprotection in Experimental Optic Neuritis, Shindler et al., 2007" that was published in The Investigative Ophthalmology and Visual Science Journal (IOVS), Volume 48, Number 8.
Optic neuritis is an eye disease, which affects the optic nerve comprised of axons emerging from the retina of the eye. The optic nerve carries visual information to the main visual nuclei, of which is primarily relayed to the outer layer of the occipital lobe of the brain; where the brain processes information into vision.
Swelling of the optic nerve can result in loss of vision more often than not because the inflammation results in destruction of the myelin sheath, which covers the optic nerve. Uninterrupted axonal damage often plays a role in neural destruction.
Optic neuritis is commonly linked to conditions including:
- Autoimmune disorders,
- Multiple sclerosis,
- Huntington disease,
- Infections, and
- Granulomatous diseases.
The scientific study at Sirtris showed, that by developing small molecule interference, eye diseases could be stopped. Sirtris hopes that he substance used in the scientific study will be approved by the FDA to treat diseases related to aging like Type II Diabetes and Macular Degeneration.
The scientific study showed that activating the SIRT1 gene, which is an enzyme in the sirtuin family, with SRT501 (resveratrol); optic neuritis be relieved. Sirtris presented pictures related to the microscopic analysis of the optic nerves of mice, which they performed; after the mice initially were induced to have optic neuritis, then anesthetized--and finally the mice had the nerves leading to the occipital injected with the SIRT1 formula.
Sirtris offered the results of the experiment as definitive proof that resveratrol could be associated with anti-aging, and that their SIRT1 a formula was a debilitating factor when used to deter some eye diseases.
Resveratrol was the agent to which the scientists assigned credit for activation of the anti-aging gene SIRT1 in mice; and they took it one step further by inferring that humans could generally, and conveniently, become accustomed to the adaptation of resveratrol as a neuroprotective agent against optic neuritis.
Therefore, Sirtris offered the study as proof that eye diseases associated with optic neuritis in humans could be stopped too, simply by using resveratrol.
The gradually loss of neurons associated with age may bring about a various debilitating neurological disorders, one of which is optic neuritis. One of the initial signs of multiple sclerosis is optic neuritis, and it's been associated with a reduction of mitochondrial function.
Sirtuin, which is a new class of enzymes and only recently discovered, appears to influence the aging process in test mammals, and Sirtris offered the study under review as proof that it increases the number and fundamental operation of mitochondria.
According to results of the scientific study, resveratrol is an SIRT1 activator and it fundamentally deterred losing retinal ganglion cells in test animals; thereby preserving axonal function in a pre-clinical model of optic neuritis.
A single intravitreal injection of SRT501, which is the proprietary resveratrol formula developed by Sirtris, was adequate for neuroprotection. What's more; the neuroprotective effect was proof that activation of SIRT1 was the reason for the significant results because that was how sirtinol, which is a SIRT1 inhibitor, was blocked.
Peter Elliott, Ph.D. said, "This work is significant because it shows that a SIRT1 activator is neuroprotective and thus has the potential to be therapeutic for a range of neurodegenerative diseases of aging."
Christoph Westphal, M.D., Ph.D., who was the Chief Executive Officer of Sirtris Pharmaceuticals, Inc. until April 2010; added, "These new data support our belief in SIRT1 as a therapeutic target for a broad range of diseases of aging including metabolic, mitochondrial, and neurological disorders."
Sirtris Pharmaceuticals, a biopharmaceutical company, is focused on inventing and developing proprietary small molecule drugs, which can be administered by physicians via intravitreal injection; and the research project under review in this expose' concerns their SRT501 resveratrol formula.
Whether or not Sirtris plans to make their SRT501 formula available as an over-the-counter supplement remains to be seen.
But the question, which will remain unanswered in this editorial; is, "Can over-the-counter resveratrol stop many of the diseases that are associated with aging simply by taking a capsule of it once or twice a day, without a prescription from a medical doctor?"
Some of the diseases, which need to be considered in a future scientific study that could provide proof that such a miracle capsule would really work to stop eye diseases, include metabolic disorders such as:
- Type 2 Diabetes,
- Alzheimer's disease,
- Optic neuritis, and
- Macular degeneration.
The study wouldn't be limited to those diseases specifically, but it will look at overall general health of individuals.
People who would like to be candidates for such a study would have to understand that the nutritional supplements, one of which would include an over-the-counter formula with a substantial amount of resveratrol, would be formulated to mimic beneficial health effects that'd ultimately be equivalent to calorie restriction; without necessitating a change of eating habits.
Activation of the newly discovered class of enzymes, sirtuin, is the foundation upon which Sirtris has offered proof via several scientific studies; that resveratrol is an anti-aging agent. The company's headquarters are in Cambridge, Massachusetts.
The press release, upon which this article is based; contained forward-looking statements, which were contained in it that conform to the Private Securities Litigation Reform Act of 1995. Those statements included, but they weren't limited to, potential therapeutic benefits of resveratrol; and they have proof that it is an SIRT1 activator.
The US Food and Drug Administration (FDA) hasn't evaluated the statements contained within this commentary. Over-the-counter resveratrol supplements are not intended to prevent, diagnose, cure or treat any disease.
The sole purpose of over-the-counter resveratrol is to activate the SIRT1 gene, which in theory would allow people to age normally without maladies commonly associated with getting older; so, as the scientific study discussed in this editorial shows, it's how some people might stop some debilitating eye diseases.
The information provided in this expose' is for educational purposes only. The information contained herein is not meant to be a substitute for medical advice of physicians, or the advice of which any other medical professionals might provide.
The accounts contained within this document shouldn't be used as a basis to diagnose or treat any health problem and/or disease; nor should any product containing resveratrol be used as a substitution for a medication that's been prescribed by your physician.
Be sure to read all product packaging and labels carefully. If you think that you could have a medical problem, promptly consult a physician or a health care provider.
February 17, 2011 Copyright of J. Michael Brown
Please, Rally round the FAITH Army.
Thank you,
J. Michael Brown, Chairman of the Board.
The FAITH Army is certified by Texas as a Domestic Nonprofit Corporation.
Please make a donation:
ACTIONS Foundation FAITH Army
J. Michael Brown, Chairman
2607 Wolflin Ave. STE #120
Amarillo TX 79109
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